Frequently Asked Questions
What is Rezulin?
Rezulin is an anti-hyperglycemic drug that increases insulin sensitivity in skeletal muscle and decreases glucose production in the liver. It helps control blood sugar levels and stimulates the body to respond better to insulin.
What was Rezulin prescribed for?
Rezulin was prescribed for patients with Type 2 (adult-onset) diabetes.
Why is Rezulin a problem?
Rezulin can cause serious liver damage (toxicity) that, in some cases, results in death. Symptoms of liver toxicity include: abdominal pain, nausea, vomiting, dark urine, jaundice, fatigue, and loss of appetite. Rezulin has also been linked to a thickening of the left ventricular wall of the heart - this condition can ultimately lead to heart failure and death.
What should I do if I took Rezulin?
If you took Rezulin to treat diabetes, you should consult your doctor immediately to discover if any damage occurred to your liver or heart. You may be entitled to monetary compensation. Contact a rezulin attorney to find out your legal rights.
Why was Rezulin recalled?
The FDA recalled Rezulin in March 2000 because it caused liver failure. Approximately 90 cases of liver failure were reported to the FDA - 63 resulted in death and 10 resulted in liver transplants. There were also some reports linking it to heart failure.
How does Rezulin cause liver damage?
Rezulin can cause liver damage through direct toxicity - dose related injury. It can also cause damage in people who are susceptible (allergic) to the drug. There has also been some evidence to suggest that damage occurred through a combination of these two factors.
Are there other drugs similar to Rezulin that I can take?
There are two drugs, Actos and Avandia, which work the same way as Rezulin but without the same side effects. The FDA recommends these two drugs for the treatment of Type 2 diabetes.
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